Thursday, February 16, 2017

Global Burden of Hepatitis C - Generic HCV Drugs Price

Hepatitis C is found worldwide. The most affected regions are Africa and Central and East Asia. Depending on the country, hepatitis C infection can be concentrated in certain populations (for example, among people who inject drugs) and/or in general populations. There are multiple strains (or genotypes) of the HCV virus and their distribution varies by region.

An estimated 2%–3% of the world's population is living with hepatitis C virus (HCV) infection, and each year, >350 000 die of HCV-related conditions, including cirrhosis and liver cancer. The burden of HCV infection varies throughout the world, with country-specific prevalence ranging from <1% to >10%. In contrast to the United States and other developed countries, HCV transmission in developing countries frequently results from exposure to infected blood in healthcare and community settings.

Hepatitis C virus (HCV) causes both acute and chronic infection. Acute HCV infection is usually asymptomatic, and is only very rarely associated with life-threatening disease. About 15–45% of infected persons spontaneously clear the virus within 6 months of infection without any treatment.

The remaining 55–85% of persons will develop chronic HCV infection. Of those with chronic HCV infection, the risk of cirrhosis of the liver is between 15–30% within 20 years.

High cost is the main barrier to expansion of CHCV (Chronic Hepatitis C Virus) treatment.

If the body is unable to fight off the virus, then Hepatiti C treatment usually involves a combination of antiviral drugs. But it is very expensive due to its patent. For some, the drugs are vastly out of reach due to their expensive prices.

GENERIC DRUGS FOR HEPATITIS C



A generic drug is the same as a brand-name drug in dosage, safety, strength, quality, the way it works, the way it is taken and the way it should be used.

The cost of Generic Drugs is 80 to 85 percent lower than the Brand name Drugs.

Please Note: Not every brand-name drug has a generic drug

Some of the HCV Medication available in market :

Wednesday, January 4, 2017

HEPATITIS C TREATMENT - TREATMENT PLAN, MEASURES TO CONTROL LIVER DAMAGE, MEDICATIONS


Treating Hepatitis C 


Hepatitis C can often be treated successfully by taking a combination of medicines for several months.

If the infection is diagnosed in the early stages, known as acute hepatitis, treatment may not need to begin straight away.
Instead, you may have another blood test after a few months to see if your body fights off the virus.
If the infection continues for several months, known as chronic hepatitis, treatment will usually be recommended.

Your treatment plan


Treatment for hepatitis C involves:
  • making lifestyle changes to help prevent further damage to your liver and reduce the risk of spreading the infection
  • taking a combination of two or three medications to fight the virus – this is known as combination therapy
You'll normally need to take medication for 12 to 48 weeks. The length of time will depend on the exact medicines you're taking. Your doctor will advise you about this.

During treatment, you should have blood tests to check if your medication is working. If the test shows treatment is having little effect, it may be stopped as further treatment may be of little use.


Lifestyle measures


There are some things you can do to help limit any damage to your liver and prevent the infection spreading to others.

These can include:
  • eating a healthy and balanced diet
  • exercising regularly
  • cutting out alcohol or limiting your intake
  • stopping smoking
  • keeping personal items, such as toothbrushes or razors, for your own use
  • not sharing any needles or syringes with others
For more information, talk to your doctor.


Hepatitis C Medications


  • Sofosbuvir
  • Daclatasvir
  • a combination of ledipasvir and sofosbuvir
  • Ribavirin, etc
Sofovir 400 mg Tablets
Ledifos Sofosbuvir Ledipasvir Tablets
MyDekla 60 mg Daclatasvir
Ribavin 200 mg Capsules

Friday, December 16, 2016

HEPATITIS C DRUGS FROM ABBOTT

About ABBOTT

Abbott Laboratories is an American worldwide health care company. It has 74,000 employees and operates in more than 150 countries. The company headquarters are in Lake Bluff, Illinois. The company was founded by Chicago physician Wallace Calvin Abbott in 1888 to formulate known drugs; it eventually grew to also sell research-based drugs, medical devices, diagnostics, and nutritional products.

Abbott has a broad range of branded generic #pharmaceuticals, medical devices, diagnostics, and nutrition products. The company's in-vitro diagnostics business performs immunoassays and blood screening. Its medical tests and diagnostic instrument systems are used worldwide by hospitals, laboratories, blood banks, and physician offices to diagnose and monitor diseases such as #HIV, #hepatitis, #cancer, heart failure and metabolic disorders, as well as assess other indicators of health. In 1985, the company developed the first HIV blood-screening test.

Abbott Laboratories has been present in India (Headquartered in Mumbai) for over 100 years through its subsidiary Abbott India Limited and it is currently India's largest healthcare products company.

ABBOTT HCV DRUGS

Generic Daclatasvir Tablets Abbott India

Dalsiclear 60 mg Tablets


Abbott Daclatasvir Tablets 60mg Details :

Brand Name : DalsiClear
Composition : Daclatasvir
Form : Tablets
Strength : 60 mg
Manufactured by : Abbott India Ltd.
Packing : Pack of 28 tablets



ViroClear Sofosbuvir 400 mg Tablets Abbott

Abbott Sofosbuvir 400 mg

ViroClear 400 mg Sofosbuvir Tablets Specification :

Brand Name : ViroClear Tablets
Content : Sofosbuvir
Form : Tablets
Strength : 400mg
Manufactured by : Abbott
Packing : Pack of 28 tablets



Ledviclear Ledipasvir Sofosbuvir Tablets

Ledviclear Ledipasvir Sofosbuvir Tablets

Ledipasvir Sofosbuvir Tablets Abbott Specification :

Brand Name : Ledviclear Tablets
Active Ingredient : Ledipasvir and Sofosbuvir
Form : Tablets
Strength : 90 mg Ledipasvir and 400 mg Sofosbuvir
Manufactured by : Abbott
Packing : Pack of 28 tablets



Tuesday, December 6, 2016

What Are the Different Stages of Hepatitis C ?

Hepatitis C is an infectious liver disease that occurs in at least 1 percent of the U.S. population. The hepatitis C virus attacks the liver, causing inflammation and scarring. Progressing in stages over the course of several decades, chronic hepatitis C is characterized by gradual and ongoing damage to the liver. In some people, the stages of the disease continue to progress until the liver can no longer function properly.


Acute Hepatitis C

The first stage of hepatitis C is known as the acute stage. During this time, the virus attacks the liver, multiplying and spreading within the liver. As the immune system attempts to fight the virus, the liver becomes inflamed. Women, younger people and those with a strong immune response are most likely to clear the virus on their own. Among people who do not clear the virus, hepatitis C becomes chronic and causes ongoing liver inflammation.

Chronic Hepatitis C

During the chronic stage of hepatitis C, viruses continue to multiply and attack liver cells as the immune system battles the infection. Infected liver cells die and new ones are generated to take their place as the liver tries to heal itself. However, the ongoing inflammation associated with the fight between the virus and the immune system leads to liver scarring, which slowly builds up over decades if hepatitis C is left untreated. This liver scarring, known as fibrosis, is a hallmark of chronic hepatitis C. Factors that tend to increase the rate of liver scarring include:
-- Male sex.
-- Infection after age 40.
-- Obesity.
-- Drinking alcohol.
-- Prediabetes and diabetes.
-- Coinfection with HIV or the hepatitis B virus.

People with chronic hepatitis C often experience no signs or symptoms despite ongoing liver inflammation and scarring. Successful treatment with direct-acting antivirals halts these harmful processes, and some liver damage might be reversible if not too extensive.

Cirrhosis

Longstanding hepatitis C can advance to cirrhosis, meaning the liver scarring is so severe that the organ's basic structure is distorted.  With early-stage cirrhosis, called compensated cirrhosis, the liver is still able to function, and the disease generally causes no symptoms.



Liver Failure

Left untreated, early-stage cirrhosis can progress to advanced cirrhosis with accompanying liver failure. With advanced-stage cirrhosis, much of the liver is supplanted by scar tissue. With advanced-stage cirrhosis, much of the liver is supplanted by scar tissue. With an inadequate number of healthy liver cells, the liver can no longer perform its many vital functions. Additionally, the buildup of scar tissue obstructs blood flow through the liver. This condition, called portal hypertension, causes a backup of blood and high pressure in the circulation that flows into the liver. The combination of poor liver function and portal hypertension causes a variety of symptoms, which might include:
-- Swelling of the abdomen due to fluid buildup.
-- Weight loss and decreased muscle tissue in the arms and legs.
-- Yellowing of the skin and whites of the eyes.
-- Easy bruising and bleeding.
-- Vomiting blood or passing bloody stools.
-- Confusion, extreme drowsiness or coma.

A liver transplant is often needed to treat people with advanced-stage cirrhosis due to hepatitis C.

Liver Cancer

Though this is not a separate stage of hepatitis C, people who develop cirrhosis because of the infection are at increased risk of developing liver cancer. The mechanisms by which hepatitis C infection causes liver cells to become cancerous are complex, but they relate to ongoing inflammation and direct interactions between the virus and liver cells.

People with advanced fibrosis or cirrhosis continue to be at increased risk for liver cancer even after successful clearance and treatment of hepatitis C virus.

Next Steps

Talk with your doctor if you are unsure whether you should be tested for hepatitis C. Contact your doctor immediately if you have any signs or symptoms of liver failure. Seek emergency medical care if you vomit blood, pass bloody or black stools or experience sudden mental changes.

Drugs For The Treatment Of Hepatitis C

Thursday, November 17, 2016

What Are the Symptoms and Warning Signs of Hepatitis C ?


Invisible disease

How do you know if you have Hepatitis C ? In the early stages of the disease it can be hard to tell, and most people don’t perceive any symptoms.

Hepatitis is an inflammation of your liver that can be very serious. Though Hepatitis can be caused by infection, medication, toxins, or autoimmune processes, it’s most commonly caused by the hepatitis viruses — in particular, hepatitis A, B, and C. The hepatitis C virus is considered the most serious out of all of the hepatitis viruses.


Types of hepatitis C

There are two main disease courses of Hepatitis C: Acute Hepatitis C and Chronic Hepatitis C. The length of time you experience symptoms will depend on the type of illness you have.

With acute hepatitis C, the symptoms are more short-term, lasting six months or less. However, acute hepatitis can lead to another type of hepatitis: chronic hepatitis. Chronic hepatitis can last for your entire life, because it’s very difficult for your body to get rid of the virus. Researchers aren’t sure why some people go on to develop the chronic form of the disease, but acute hepatitis C infections often progress to the chronic infection.


How can I tell ?

People with acute Hepatitis C will not experience symptoms. In some cases, people will experience symptoms not long after the virus has infected them.

These symptoms can be mild or severe and include:
  • fever
  • feeling tired
  • poor appetite

More warning signs

If you develop Hepatitis C symptoms soon after infection, you might also have these symptoms:
  • nausea or vomiting
  • pain in your stomach
  • joint or muscle pain
  • abnormalities in urine or bowel movements
  • a yellowing in your eyes or skin
Early symptoms would be most likely to occur around six or seven weeks after exposure to the hepatitis C virus.

Getting Diagnosed

Since it can be difficult to tell based on symptoms whether you have contracted Hepatitis C, you can be tested for it. A simple blood test in your doctor’s office or lab can confirm whether you have the condition.

After your doctor gets the results of your blood test, they may recommend that you undergo a biopsy on your liver to determine if you have chronic hepatitis C.


Treating the Symptoms

If you do have symptoms of hepatitis C, there are Treatments available. Your doctor may prescribe medications to prevent damage to your liver. By monitoring your symptoms closely and performing blood tests, your doctor can confirm whether certain treatments are working for you.

In the past, there was no medication to rid Hepatitis C. However, over the last few years more medications have been approved to treat this disease. Your primary care doctor will most likely refer you to a liver specialist who can help you determine the best course of treatment.

There are some Medicines which are used in treatment of Hepatitis C, such as :

Thursday, October 20, 2016

The Effects of Hepatitis C on the Body

Hepatitis C is caused by a #virus that is passed through contact with the blood of an infected person. The infection leads to inflammation of the #liver.

The liver processes blood and filter toxins so they don’t cause damage to your body. The liver also produces bile, which helps you to digest food and stores glucose and vitamins. Inflammation makes it difficult for the liver to perform these vital functions. In time, the #hepatitisC infection can affect the entire body.

Hepatitis C Effects On Body

Early #symptoms, including yellowing skin and fatigue, may be mild and easily dismissed. Chronic #infection can cause scarring of the liver (cirrhosis). As the #disease progresses, symptoms such as #skin problems, blood disorders, and #fever may appear.

In the long term, #hepatitis C can lead to severe liver damage, liver #cancer, and liver failure. Early #treatment can help delay or prevent serious damage.

Digestive System


Inflammation of the gallbladder can make it painful to digest fatty foods. Therefore, people with hepatitis C may feel some pain in the upper right portion of the #abdomen. This may be due to a build-up of fluid in the #stomach (ascites). This occurs when the damaged liver doesn’t produce enough albumin, a substance that regulates the amount of fluid in cells.

Other digestive symptoms include #nausea, #vomiting, and #lossofappetite. Stool may become pale or clay-colored, and urine may darken.

Central Nervous System


When the liver doesn’t filter toxins from the blood, they can damage the central #nervoussystem (hepatic encephalopathy). This can lead to a variety of symptoms, including sweet or musty breath, weakening of small motor skills, and sleep disturbances. Dry #eyes and mouth are sometimes associated with hepatitis C.

A build-up of #toxins in the brain can cause confusion, #forgetfulness, poor concentration, and personality changes. Advanced symptoms include abnormal shaking, agitation, #disorientation, and slurred speech. Severe cases may cause #coma.

Circulatory System


A poorly functioning liver can create blood flow problems and increase pressure in the #vein that leads to the liver (portal vein). This can cause portal #hypertension, which may force blood to find an alternate vein. The vein can burst if it’s too small, causing serious internal #bleeding (variceal bleeding).

Skin, Hair, and Nails (Integumentary System)


A protein molecule called hemoglobin is found in red blood cells. #Hemoglobin transports #oxygen and #iron to cells throughout the body. Iron is crucial in sustaining cells that make up healthy skin, fingernails, toenails, and hair.
Bilirubin is another important substance in hemoglobin. When the liver can’t do its job, bilirubin can build up and cause your skin and the whites of your eyes to turn yellow.

Endocrine and Immune Systems


The #endocrine system regulates #hormones. As part of the endocrine system, the #thyroid gland delivers hormones into the bloodstream. Sometimes hepatitis C can cause the #immunesystem to mistakenly attack or damage thyroid tissue. This can cause an overactive thyroid (hyperthyroidism), which can lead to #sleepdisorders and #weightloss. Underactive thyroid (hypothyroidism) can make you feel sluggish.

Overall Health

Many people infected with hepatitis C have no symptoms, especially in the earliest stages. Some report general #fatigue, #fever, or non-specific #aches and #pains.

DRUGS USED For TREATMENT OF HEPATITIS C
Find Complete List of Hepatitis C Generic and Branded Medicines here with complete details about medicine.

Content Source : HealthLine

Monday, September 26, 2016

10 Essential Facts About Hepatitis C

Hepatitis C is a viral infection that damages your liver over time. A chronic infection can lead to serious scarring of the liver called cirrhosis, as well as liver cancer and liver failure. Hepatitis C treatment used to be a lengthy process that was not very effective. Now, groundbreaking new medicines have turned the viral infection into a curable condition; hepatitis C is considered "cured" when the virus is not detectable at 12 and 24 weeks after treatment ends.

Here are 10 essential facts you should know about hepatitis C:

  • Hepatitis C affects millions of Americans. About 2.7 million people in the United States have chronic hepatitis C.
  • The most common hepatitis C strain in the United States is genotype 1. The hepatitis C virus is diverse and includes six commonly-seen types. About 75 percent of hepatitis C cases here are genotype 1, and 12 percent are genotype 2, with fewer cases of genotypes 3 to 6.
  • You might not realize you have serious liver damage. In some cases, by the time you have hepatitis C symptoms, life-threatening damage has already occurred.
  • The hepatitis C virus is spread by contact with infected blood. Healthcare workers accidentally stuck with contaminated needles and babies born to hepatitis-infected mothers are among those at risk. Sharing needles for drug use or getting tattoos or piercings using unsterile equipment are the typical ways of getting a new hepatitis C infection today.
  • All baby boomers need to get a hepatitis C test.
  • There is no hepatitis C vaccine. A vaccine is not yet available because there are many different kinds of hepatitis C, and it’s difficult to come up with one vaccine that's effective in preventing them all. Avoiding high-risk behaviors, like sharing needles, is still the best way to avoid getting infected.
  • Hepatitis C treatment is advancing rapidly
  • If you have hepatitis C, simple precautions can protect others. Do not share personal items that could have even tiny amounts of blood, like toothbrushes, razors, clippers, etc. Clean up any spilled blood right away with a solution of bleach and water. Cover blisters or cuts with bandages, and carefully dispose of anything with blood on it, like bandages or tampons
  • Even after you are cured of the virus, you still need checkups
  • A liver transplant is not a cure for hepatitis C. Even after a liver transplant, medication is needed to remove Hepatitis virus. It's possible to become infected again.



Medicines Commonly Used in Treatment of Hepatitis C



To get full list of Hepatitis C Medicine, visit :- http://www.oddwayinternational.com/hepatitis-medicine

Content Source :- EveryDayHealth